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Rabbit Anti-FBG4  antibody (bs-16031R)  
~~~促銷代碼KT202411~~~
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產品編號 bs-16031R
英文名稱 Rabbit Anti-FBG4  antibody
中文名稱 FBG4蛋白抗體
別    名 F box only protein 17; F box only protein 26; F-box only protein 17; F-box only protein 26; F-box protein 17; F-box protein FBG4; FBX17; FBX17_HUMAN; FBX26; Fbxo17; FBXO26; FLJ11798; FLJ25205; FLJ58300; MGC9379.  
研究領域 細胞生物  免疫學  神經生物學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse,Rat,Rabbit,Cow,Dog)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 31kDa
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FBG4: 61-160/278 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 This gene encodes a member of the F-box protein family which is characterized by the F-box motif. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it contains an F-box domain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

Function:
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Able to recognize and bind denatured glycoproteins, which are modified with complex-type oligosaccharides. Also recognizes sulfated glycans. Does not bind high-mannose glycoproteins.

Tissue Specificity:
Expressed in heart, skeletal muscle, liver and kidney. Expressed at lower levels in spleen and brain.

Similarity:
Contains 1 F-box domain.
Contains 1 FBA (F-box associated) domain.

SWISS:
Q96EF6

Gene ID:
115290

Database links:

Entrez Gene: 115290 Human

Entrez Gene: 50760 Mouse

Entrez Gene: 292757 Rat

GenBank: NM_024907 Human

GenBank: NM_148169 Human

GenBank: NM_015796 Mouse

Omim: 609094 Human

SwissProt: Q96EF6 Human

SwissProt: Q9QZM8 Mouse

SwissProt: Q6AY27 Rat

Unigene: 531770 Human

Unigene: 358659 Mouse

Unigene: 53606 Rat



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