| 產(chǎn)品編號(hào) | bs-14646R |
| 英文名稱 | Rabbit Anti-KCNIP4 antibody |
| 中文名稱 | A型鉀離子通道調(diào)節(jié)蛋白4抗體 |
| 別 名 | A type potassium channel modulatory protein 4; a-type potassium channel modulatory protein 4; CALP; calsenilin like protein; Calsenilin-like protein; HGNC:30083; KCHIP 4; KCHIP4; KCIP4_HUMAN; KCNIP 4; Kcnip4; Kv channel interacting protein 4; Kv channel-interacting protein 4; MGC44947; Potassium channel interacting protein 4; Potassium channel-interacting protein 4. |
| 研究領(lǐng)域 | 細(xì)胞生物 神經(jīng)生物學(xué) 通道蛋白 |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Cow,Dog) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 29kDa |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human KCNIP4: 41-140/250 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. This protein member also interacts with presenilin. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] Function: Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Probably modulates channels density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner. In vitro, modulates KCND2/Kv4.2 and KCND3/Kv4.3 currents. Subcellular Location: Cell membrane. Tissue Specificity: Predominantly expressed in brain. Similarity: Belongs to the recoverin family. Contains 4 EF-hand domains. SWISS: Q6PIL6 Gene ID: 80333 Database links: Entrez Gene: 80333 Human Entrez Gene: 80334 Mouse Omim: 608182 Human SwissProt: Q6PIL6 Human SwissProt: Q6PHZ8 Mouse Unigene: 655705 Human Unigene: 160172 Mouse Unigene: 205864 Rat |
