| 產(chǎn)品編號(hào) | bs-14614R |
| 英文名稱 | Rabbit Anti-EPHX1 antibody |
| 中文名稱 | 環(huán)氧化物水解酶1抗體 |
| 別 名 | HYEP_HUMAN; Epoxide hydrolase 1; EC:3.3.2.9; Epoxide hydratase; Microsomal epoxide hydrolase (mEH); EPHX, EPOX; HYL1; EPHX 1; |
| 研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 新陳代謝 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Horse) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 53kDa |
| 細(xì)胞定位 | 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human EPHX1: 21-120/455 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Epoxide hydrolase is a critical biotransformation enzyme that converts epoxides from the degradation of aromatic compounds to trans-dihydrodiols which can be conjugated and excreted from the body. Epoxide hydrolase functions in both the activation and detoxification of epoxides. Mutations in this gene cause preeclampsia, epoxide hydrolase deficiency or increased epoxide hydrolase activity. Alternatively spliced transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Dec 2008] Function: Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. Subcellular Location: Microsome membrane. Endoplasmic reticulum membrane. Tissue Specificity: Found in liver. DISEASE: Note=In some populations, the high activity haplotype tyr113/his139 is overrepresented among women suffering from pregnancy-induced hypertension (pre-eclampsia) when compared with healthy controls. Defects in EPHX1 are a cause of familial hypercholanemia (FHCA) [MIM:607748]. FHCA is a disorder characterized by elevated serum bile acid concentrations, itching, and fat malabsorption. Similarity: Belongs to the peptidase S33 family. SWISS: P07099 Gene ID: 2052 Database links: Entrez Gene: 2052 Human Entrez Gene: 13849 Mouse Omim: 132810 Human SwissProt: P07099 Human SwissProt: Q9D379 Mouse Unigene: 89649 Human Unigene: 9075 Mouse Unigene: 3603 Rat |
