| 產(chǎn)品編號(hào) | bs-14592R |
| 英文名稱 | Rabbit Anti-ENDOGL1 antibody |
| 中文名稱 | 核酸內(nèi)切酶G樣蛋白1抗體 |
| 別 名 | Endo G like 1; Endo G-like 1; ENDOGL 1; ENDOGL2; Endonuclease G like 1; Endonuclease G-like 1; ENGL a; ENGL; ENGL B; EXOG; EXOG_HUMAN; MGC125944; MGC125945; mitochondrial; Nuclease EXOG; Nuclease EXOG mitochondrial. |
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Specific References (1) | bs-14592R has been referenced in 1 publications.
[IF=2.678] Jingsong Xiao. et al. PGC-1ɑ Mediated-EXOG, a Specific Repair Enzyme for Mitochondrial DNA, Plays an Essential Role in the Rotenone-Induced Neurotoxicity of PC12 Cells. 2021 Jan 30 IF ;
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| 研究領(lǐng)域 | 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 新陳代謝 表觀遺傳學(xué) |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Chicken) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 41kDa |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ENDOGL1: 51-150/368 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene encodes an endo/exonuclease with 5'-3' exonuclease activity. The encoded enzyme catalyzes the hydrolysis of ester linkages at the 5' end of a nucleic acid chain. This enzyme is localized to the mitochondria and may play a role in programmed cell death. Alternatively spliced transcript variants have been described. A pseudogene exists on chromosome 18. [provided by RefSeq, Feb 2009] Function: Endo/exonuclease with nicking activity towards supercoiled DNA, a preference for single stranded DNA and 5'-3' exonuclease activity. Subcellular Location: Mitochondrion inner membrane. Tissue Specificity: Ubiquitous. Similarity: Belongs to the DNA/RNA non-specific endonuclease family. SWISS: Q9Y2C4 Gene ID: 9941 Database links: Entrez Gene: 9941 Human Entrez Gene: 208194 Mouse Omim: 604051 Human SwissProt: Q9Y2C4 Human SwissProt: Q8C163 Mouse Unigene: 517897 Human Unigene: 101578 Mouse |
