| 產(chǎn)品編號(hào) | bs-14539R |
| 英文名稱 | Rabbit Anti-EIF2D antibody |
| 中文名稱 | EIF2D蛋白抗體 |
| 別 名 | Eukaryotic translation initiation factor 2D; HCA56; Hepatocellular carcinoma associated antigen 56; Hepatocellular carcinoma-associated antigen 56; LGTN; LIGA_HUMAN; Ligatin; OTTHUMP00000034537; OTTHUMP00000034538. |
| 研究領(lǐng)域 | 細(xì)胞生物 發(fā)育生物學(xué) 轉(zhuǎn)運(yùn)蛋白 細(xì)胞粘附分子 細(xì)胞分化 新陳代謝 |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Pig,Cow) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 65kDa |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human EIF2D: 11-110/584 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
HCA56 is a 584 amino acid peripheral membrane protein belonging to the ligatin family. Expressed during embryonic development and in early differentiated states, ligatin is a trafficking receptor for phosphoglycoproteins. Ligatin localizes to phosphoglycoproteins within endosomes and at the cell periphery where it participates in specific metabolic processes as well as intercellular adhesion. Involved in RNA binding and translation initiation through its single PUA domain and SUI1 domain, ligatin is down-regulated with long-lasting effects by the activation of Ca2+ dependent N-methyl-D-aspartate (NMDA) subclass of excitatory amino acid (EAA) receptors. Ligatin is considered a marker protein for membrane-vesicle transport systems. Ligatin exists as two alternatively splice variants and is encoded by a gene located on human chromosome 1. Function: Trafficking receptor for phosphoglycoproteins. Localizes phosphoglycoproteins within endosomes and at the cell periphery where they participate in specific metabolic processes as well as intercellular adhesion. Subcellular Location: Membrane. Similarity: Belongs to the ligatin family. Contains 1 PUA domain. Contains 1 SUI1 domain. SWISS: P41214 Gene ID: 1939 Database links: Entrez Gene: 1939 Human Omim: 151625 Human SwissProt: P41214 Human Unigene: 497581 Human |
