| 產(chǎn)品編號(hào) | bs-14496R |
| 英文名稱 | Rabbit Anti-EBPL antibody |
| 中文名稱 | EBPL蛋白抗體 |
| 別 名 | Delta8-delta7 sterol isomerase related protein; EBPL; EBPL_HUMAN; EBRP; Emopamil binding protein like; Emopamil binding related protein; Emopamil-binding protein-like. |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 免疫學(xué) 神經(jīng)生物學(xué) |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 23kDa |
| 細(xì)胞定位 | 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human EBPL: 51-150/206 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
EBPL is expressed as a homodimer with high levels found in liver, lung and kidney. As a transmembrane protein embedded on the endoplasmic reticulum, EBPL may function as a cholestenol delta-isomerase. The gene encoding EBPL is found on human chromosome 13. Comprising nearly 4% of the human genome, chromosome 13 contains around 114 million base pairs and encodes over 400 genes. Chromosome 13 houses key tumor suppressor genes, including BRCA2 and RB1, which are associated with breast cancer susceptibility and retinoblastoma, respectively. Trisomy 13, also known as Patau syndrome, is deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections. Function: Does not possess sterol isomerase activity and does not bind sigma ligands. Subunit: Homodimer. Subcellular Location: Endoplasmic reticulum membrane; Multi-pass membrane protein. Tissue Specificity: Widely expressed with highest levels in liver, lung and kidney. Similarity: Belongs to the EBP family. SWISS: Q9BY08 Gene ID: 84650 Database links: Entrez Gene: 84650 Human SwissProt: Q9BY08 Human Unigene: 433278 Human |
