| 產(chǎn)品編號 | bs-14442R |
| 英文名稱 | Rabbit Anti-NCALD antibody |
| 中文名稱 | 神經(jīng)鈣蛋白NCALD抗體 |
| 別 名 | MGC33870; MGC74858; NCALD; NCALD_HUMAN; Neurocalcin delta; Neurocalcin-delta. |
| 研究領(lǐng)域 | 細(xì)胞生物 神經(jīng)生物學(xué) 結(jié)合蛋白 G蛋白信號 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Cow,Chicken) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 22kDa |
| 細(xì)胞定位 | 細(xì)胞漿 細(xì)胞外基質(zhì) 分泌型蛋白 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human NCALD: 51-150/193 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene encodes a member of the neuronal calcium sensor (NCS) family of calcium-binding proteins. The protein contains an N-terminal myristoylation signal and four EF-hand calcium binding loops. The protein is cytosolic at resting calcium levels; however, elevated intracellular calcium levels induce a conformational change that exposes the myristoyl group, resulting in protein association with membranes and partial co-localization with the perinuclear trans-golgi network. The protein is thought to be a regulator of G protein-coupled receptor signal transduction. Several alternatively spliced variants of this gene have been determined, all of which encode the same protein; additional variants may exist but their biological validity has not been determined. [provided by RefSeq, Jul 2008] Function: May be involved in the calcium-dependent regulation of rhodopsin phosphorylation. Binds three calcium ions. Tissue Specificity: Retina, cerebrum, cerebellum, brain stem, spinal cord, testis, ovary and small intestine. Similarity: Belongs to the recoverin family. Contains 4 EF-hand domains. SWISS: P61601 Gene ID: 83988 Database links: Entrez Gene: 83988 Human Entrez Gene: 52589 Mouse Omim: 606722 Human SwissProt: P61601 Human SwissProt: Q91X97 Mouse Unigene: 492427 Human Unigene: 680132 Human Unigene: 283370 Mouse Unigene: 13744 Rat |
