| 產(chǎn)品編號(hào) | bs-14290R |
| 英文名稱 | Rabbit Anti-DGAT2L4 antibody |
| 中文名稱 | 二酰基甘油?；D(zhuǎn)移酶2樣蛋白4抗體 |
| 別 名 | Acyl CoA wax alcohol acyltransferase 2; acyl-CoA retinol O-fatty-acyltransferase; ARAT; AWAT2; DC4; Diacylglycerol O acyltransferase 2 like 4; Diacylglycerol O acyltransferase candidate 4; diacylglycerol O-acyltransferase 2-like protein 4; hWS; Long chain alcohol O fatty acyltransferase 2; MFAT; Multifunctional O acyltransferase; retinol O-fatty-acyltransferase; Wax synthase 2; Wax synthase; WS. |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 新陳代謝 |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat) |
| 產(chǎn)品應(yīng)用 | ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 38kDa |
| 細(xì)胞定位 | 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human DGAT2L4: 251-333/333 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene encodes an enzyme belonging to the diacylglycerol acyltransferase family. This enzyme produces wax esters by the esterification of long chain (or wax) alcohols with acyl-CoA-derived fatty acids. It functions in lipid metabolism in the skin, mostly in undifferentiated peripheral sebocytes. This enzyme may also have acyl-CoA:retinol acyltransferase activities, where it catalyzes the synthesis of diacylglycerols and retinyl esters. [provided by RefSeq, May 2010] Function: Acyltransferase that predominantly esterify long chain (wax) alcohols with acyl-CoA-derived fatty acids to produce wax esters. Wax esters are enriched in sebum, suggesting that it plays a central role in lipid metabolism in skin. Has no activity using decyl alcohol and significantly prefers the C16 and C18 alcohols. May also have 2 acylglycerol O acyltransferase (MGAT) and acyl-CoA:retinol acyltransferase (ARAT) activities, to catalyze the synthesis of diacylglycerols and retinyl esters; however this activity is unclear in vivo. Subcellular Location: Endoplasmic reticulum membrane; Multipass membrane protein. Tissue Specificity: Abundant in tissues rich in sebaceous glands such as the preputial gland and eyelid. Highly expressed in skin, where it is primarily restricted to undifferentiated peripheral sebocytes. Also expressed at lower level in other tissues except pancreas. Similarity: Belongs to the diacylglycerol acyltransferase family. SWISS: Q6E213 Gene ID: 158835 Database links: Entrez Gene: 158835 Human Entrez Gene: 245532 Mouse SwissProt: Q6E213 Human SwissProt: Q6E1M8 Mouse Unigene: 661507 Human Unigene: 118171 Mouse Unigene: 220750 Rat |
