| 產(chǎn)品編號 | bs-14203R |
| 英文名稱 | Rabbit Anti-DBNDD2/CK1BP antibody |
| 中文名稱 | 酪蛋白激酶1結(jié)合蛋白抗體 |
| 別 名 | C20orf35; Casein kinase-1 binding protein; CK1BP; DBND2_HUMAN; Dbndd2; Dysbindin (dystrobrevin binding protein 1) domain containing 2; Dysbindin domain-containing protein 2; HSMNP1; SCF apoptosis response protein 1. |
| 研究領(lǐng)域 | 細(xì)胞生物 神經(jīng)生物學(xué) 激酶和磷酸酶 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 28kDa |
| 細(xì)胞定位 | 細(xì)胞核 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human DBNDD2/CK1BP: 151-259/259 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
CK1BP is a 261 amino acid member of the dysbindin family and is a paralog of dysbindin, a protein trafficking protein involved in lysosome biosynthesis that has been associated with schizophrenia and muscular dystrophy. Human and rat HSMNP1 share 86% identity and both proteins contain three casein kinase II and PKC (protein kinase C) phosphorylation sites, a putative N-glycosylation site and a PEST motif at the C-terminus. HSMNP1 is a cytoplasmic protein and it specifically localizes to vesicles during the induction of apoptosis. In addition, HSMNP1 may be involved in normal as well as pathological myeloid development. Two isoforms of HSMNP1 exist due to alternative splicing events. Function: May modulate the activity of casein kinase-1. Inhibits CSNK1D autophosphorylation (in vitro). Tissue Specificity: Detected in brain. Similarity: Belongs to the dysbindin family. SWISS: Q9BQY9 Gene ID: 55861 Database links: Entrez Gene: 55861 Human Omim: 611453 Human SwissProt: Q9BQY9 Human Unigene: 655055 Human |
