| 產(chǎn)品編號(hào) | bs-14190R |
| 英文名稱 | Rabbit Anti-DAGLB antibody |
| 中文名稱 | 二?；视椭久甫?DAGLβ 抗體 |
| 別 名 | Daglb; DGL beta; DGL-beta; DGLB_HUMAN; Diacylglycerol lipase beta; KCCR13L; Sn1 specific diacylglycerol lipase beta; Sn1-specific diacylglycerol lipase beta. |
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Specific References (2) | bs-14190R has been referenced in 2 publications.
[IF=4.36] Xiao Li. et al. Mechanism by which Huoxue Tongluo Qiwei Decoction improves the erectile function of rats with diabetic erectile dysfunction. J Ethnopharmacol. 2022 Jan;283:114674 WB ; Rat.
[IF=3.69] Ji-Sheng Wang. et al. Effect of leech-centipede medicine on improving erectile function in DIED rats via PKC signalling pathway-related molecules. J Ethnopharmacol. 2021 Mar;267:113463 WB ; Rat.
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| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 新陳代謝 |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Mouse (predicted: Human,Rat,Rabbit,Pig,Sheep,Cow) |
| 產(chǎn)品應(yīng)用 | ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 74kDa |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human DAGLB: 51-150/672 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
KCCR13L, is a 672 amino acid multi-pass membrane protein that belongs to the AB hydrolase superfamily. DAGL beta uses calcium as a cofactor to catalyze the hydrolysis of diacylglycerol (DAG) to 2-arachidonoyl-glycerol (2-AG), a reaction that is required for axonal growth and for retrograde synaptic signaling at mature synapses. DAGL beta functions at an optimal pH of 7 and its activity is inhibited by p-hydroxy-mercuri-benzoate and HgCl2, but not PMSF. There are three isoforms of DAGL beta that are produced as a result of alternative splicing events. Function: Catalyzes the hydrolysis of diacylglycerol (DAG) to 2-arachidonoyl-glycerol (2-AG), the most abundant endocannabinoid in tissues. Required for axonal growth during development and for retrograde synaptic signaling at mature synapses. Subcellular Location: Cell membrane. Similarity: Belongs to the AB hydrolase superfamily. Lipase family. SWISS: Q8NCG7 Gene ID: 221955 Database links: Entrez Gene: 221955 Human Entrez Gene: 231871 Mouse SwissProt: Q8NCG7 Human SwissProt: Q91WC9 Mouse Unigene: 487498 Human Unigene: 469963 Mouse |
