產(chǎn)品編號(hào) | bs-14130R |
英文名稱 | Rabbit Anti-CYB5D1 antibody |
中文名稱 | 細(xì)胞色素B5結(jié)構(gòu)域蛋白1抗體 |
別 名 | CYB5D 1; Cytochrome b5 domain containing 1; Cytochrome b5 domain containing protein 1; FLJ32499; Gm740; MGC118302; RP23 5O23.2; CB5D1_HUMAN. |
研究領(lǐng)域 | 腫瘤 細(xì)胞生物 新陳代謝 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Human (predicted: Mouse,Rat,Sheep,Cow,Dog,Horse) |
產(chǎn)品應(yīng)用 | WB=1:500-2000,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 27kDa |
細(xì)胞定位 | 細(xì)胞核 細(xì)胞漿 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human CYB5D1: 42-150/228 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
Cytochrome b5 is a membrane-bound heme protein that possesses two heme groups and functions as an electron carrier for many membrane-bound oxygenases. Two isoforms of cytochrome b5, a microsomal membrane-bound form and a cytoplasmic form, are produced by alternative splicing. Mutations in the gene encoding cytochrome b5 are associated with Leber’s hereditary optic neuropathy and myopathy. CYB5D1 (cytochrome b5 domain containing 1) is a 228 amino acid protein that exists as two alternatively spliced variants and contains one cytochrome b5 heme-binding domain, suggesting a similar function to cytochrome b5. The gene encoding CYB5D1 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Function: CYB5D1 belongs to the cytochrome b5 family and contains 1 cytochrome b5 heme-binding domain. Cytochromes b5 are ubiquitous electron transport proteins found in animals, plants and yeasts. There are 2 named isoforms produced by alternative splicing. SWISS: Q6P9G0 Gene ID: 124637 Database links: Entrez Gene: 124637 Human SwissProt: Q6P9G0 Human Unigene: 27475 Human |