產(chǎn)品編號 | bs-13940R |
英文名稱 | Rabbit Anti-CHST9 antibody |
中文名稱 | 碳水化合物磺基轉(zhuǎn)移酶8抗體 |
別 名 | Carbohydrate (N acetylgalactosamine 4 0) sulfotransferase 8; Carbohydrate sulfotransferase 8; CHST 8; GalNAc 4 O sulfotransferase 1; GalNAc 4 ST1; CHST9_HUMAN; GalNAc4ST 1; GalNAc4ST; GALNAC4ST1; N acetylgalactosamine 4 O sulfotransferase 1; N acetylgalactosamine 4 O sulfotransferase. |
研究領(lǐng)域 | 信號轉(zhuǎn)導(dǎo) 生長因子和激素 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Human (predicted: Mouse,Rabbit,Horse) |
產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 52kDa |
細(xì)胞定位 | 細(xì)胞漿 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human CHST9: 351-443/443 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
The protein encoded by this gene belongs to the sulfotransferase 2 family. It is localized to the golgi membrane, and catalyzes the transfer of sulfate to position 4 of non-reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans. Sulfate groups on carbohydrates confer highly specific functions to glycoproteins, glycolipids, and proteoglycans, and are critical for cell-cell interaction, signal transduction, and embryonic development. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Aug 2011] Function: Catalyzes the transfer of sulfate to position 4 of non-reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans. Participates in biosynthesis of glycoprotein hormones lutropin and thyrotropin, by mediating sulfation of their carbohydrate structures. Has a higher activity toward carbonic anhydrase VI than toward lutropin. Only active against terminal GalNAcbeta1,GalNAcbeta. Isoform 2, but not isoform 1, is active toward chondroitin. Subcellular Location: Secreted and Golgi apparatus membrane. Tissue Specificity: Highly expressed in trachea. Also expressed in fetal lung, adult pancreas, testis and salivary gland. Expressed at low level in pituitary gland, apex of the heart, adult lung, prostate and mammary gland. Weakly or not expressed in heart, liver and spinal cord. Similarity: Belongs to the sulfotransferase 2 family. SWISS: Q7L1S5 Gene ID: 83539 Database links: Entrez Gene: 83539 Human Entrez Gene: 71367 Mouse Omim: 610191 Human SwissProt: Q7L1S5 Human SwissProt: Q76EC5 Mouse Unigene: 44584 Human Unigene: 706552 Human Unigene: 329304 Mouse |
產(chǎn)品圖片 |
Sample:
HepG2 (human)Cell Lysate at 40 ug
MDA-MB-231 (human)Cell Lysate at 40 ug
Primary: Anti-CHST9(bs-13940R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 52 kD
Observed band size: 52 kD
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