| 產(chǎn)品編號 | bs-13939R |
| 英文名稱 | Rabbit Anti-CHST8 antibody |
| 中文名稱 | 碳水化合物磺基轉(zhuǎn)移酶8抗體 |
| 別 名 | Carbohydrate (N acetylgalactosamine 4 0) sulfotransferase 8; Carbohydrate sulfotransferase 8; CHST 8; GalNAc 4 O sulfotransferase 1; GalNAc 4 ST1; CHST8_HUMAN; GalNAc4ST 1; GalNAc4ST; GALNAC4ST1; N acetylgalactosamine 4 O sulfotransferase 1; N acetylgalactosamine 4 O sulfotransferase. |
| 研究領(lǐng)域 | 細(xì)胞生物 生長因子和激素 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human,Mouse (predicted: Rat,Rabbit,Pig,Cow,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 49kDa |
| 細(xì)胞定位 | 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human CHST9: 141-240/424 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
The protein encoded by this gene belongs to the sulfotransferase 2 family. It is predominantly expressed in the pituitary gland, and is localized to the golgi membrane. This protein catalyzes the transfer of sulfate to position 4 of non-reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans. It is responsible for sulfation of GalNAc on luteinizing hormone (LH), which is required for production of the sex hormones. Mice lacking this enzyme, exhibit increased levels of circulating LH, and precocious sexual maturation of both male and female mice. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2011] Function: CHST8, or Carbohydrate sulfotransferase 8, catalyzes the transfer of sulfate to position 4 of non-reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans. It is required for biosynthesis of glycoprotein hormones lutropin and thyrotropin, by mediating sulfation of their carbohydrate structures. CHST8 is only active against terminal GalNAcbeta1 and GalNAcbeta and not toward chondroitin. Subcellular Location: Golgi apparatus membrane; Single-pass type II membrane protein. Similarity: Belongs to the sulfotransferase 2 family. SWISS: Q9H2A9 Gene ID: 64377 Database links: Entrez Gene: 64377 Human Entrez Gene: 68947 Mouse Omim: 610190 Human SwissProt: Q9H2A9 Human SwissProt: Q8BQ86 Mouse Unigene: 165724 Human Unigene: 29380 Mouse Unigene: 55646 Rat |
| 產(chǎn)品圖片 |
Sample:Uterus (Mouse) Lysate at 40 ug
Primary: Anti-CHST8(bs-13939R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 49kD
Observed band size: 59kD
Sample:Hela(human) Cell Lysate at 40 ug
Primary: Anti-CHST8(bs-13939R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 49kD
Observed band size: 59kD
|
