產(chǎn)品編號(hào) | bs-13921R |
英文名稱 | Rabbit Anti-Choline kinase alpha antibody |
中文名稱 | 乙醇胺激酶α抗體 |
別 名 | CHETK alpha; CHETK-alpha; CHK; CHKA; CK; CKI; EK; Ethanolamine kinase; CHKA_HUMAN. |
研究領(lǐng)域 | 腫瘤 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 新陳代謝 |
抗體來(lái)源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human,Mouse,Rat,Pig,Sheep,Cow,Dog) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 52kDa |
細(xì)胞定位 | 細(xì)胞漿 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human Choline kinase alpha: 151-250/457 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
The major pathway for the biosynthesis of phosphatidylcholine occurs via the CDP-choline pathway. The protein encoded by this gene is the initial enzyme in the sequence and may play a regulatory role. The encoded protein also catalyzes the phosphorylation of ethanolamine. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Function: The dominant pathway for biosynthesis of phosphatidylcholine occurs through the CDP-choline pathway. Choline kinase alpha (CHK) is the first enzyme in the pathway and may thereby play an upstream regulatory role in lipid transport and metabolism. CHK additionally catalyzes phosphorylation of ethanolamine. Subunit: Heterodimer with CHKB (By similarity). Homodimer. Subcellular Location: Cytoplasmic Similarity: Belongs to the choline/ethanolamine kinase family. SWISS: P35790 Gene ID: 1119 Database links: Entrez Gene: 1119 Human Entrez Gene: 12660 Mouse Omim: 118491 Human SwissProt: P35790 Human SwissProt: O54804 Mouse Unigene: 77221 Human Unigene: 225505 Mouse Unigene: 10985 Rat |