| 產(chǎn)品編號 | bs-13758R |
| 英文名稱 | Rabbit Anti-C21orf66 antibody |
| 中文名稱 | 21號染色體開放閱讀框66抗體 |
| 別 名 | BM 020; BM020; Chromosome 21 open reading frame 66; FSAP105; Functional spliceosome-associated protein 105; GC rich sequence DNA binding factor candidate; GC-rich sequence DNA-binding factor 1; GCFC; GCFC1; PAXB1_HUMAN; PAX3 and PAX7 binding protein 1; PAXBP1. |
| 研究領(lǐng)域 | 細(xì)胞生物 神經(jīng)生物學(xué) 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Sheep,Cow,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 105kDa |
| 細(xì)胞定位 | 細(xì)胞核 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human C21orf66: 101-200/917 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
C21orf66, also known as GCFC (GC-rich sequence DNA-binding factor), is a 917 amino acid protein that localizes to the nucleus and belongs to the GCF family. Expressed ubiquitously, C21orf66 functions as a possible transcription factor and exists as four alternatively spliced isoforms, designated A, B, C and D. The gene encoding C21orf66 maps to human chromosome 21, which houses approximately 300 genes and comprises nearly 1.5% of the human genome. Chromosome 21-associated disorders include Alzheimer's Disease, amyotrophic lateral sclerosis and, most notably, Down Syndrome (also known as trisomy 21. Function: Possible transcription factor. Subcellular Location: Nucleus. Tissue Specificity: Ubiquitous. Similarity: Belongs to the GCF family. SWISS: Q9Y5B6 Gene ID: 94104 Database links: Entrez Gene: 94104 Human SwissProt: Q9Y5B6 Human Unigene: 644004 Human |
