產(chǎn)品編號(hào) | bs-15560R |
英文名稱 | Rabbit Anti-IFT172 antibody |
中文名稱 | 細(xì)胞纖毛內(nèi)轉(zhuǎn)運(yùn)同源蛋白172抗體 |
別 名 | IF172_HUMAN; ift172; Intraflagellar transport 172 homolog (Chlamydomonas); Intraflagellar transport protein 172 homolog; Osm 1; Selective LIM binding factor homolog; SLB; Wim; Wimple homolog. |
研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 轉(zhuǎn)運(yùn)蛋白 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Pig,Cow,Chicken,Dog,Horse) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 198kDa |
細(xì)胞定位 | 分泌型蛋白 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human IFT172: 1-100/1749 |
亞 型 | |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
This gene encodes a subunit of the intraflagellar transport subcomplex IFT-B. Subcomplexes IFT-A and IFT-B are necessary for ciliary assembly and maintenance. Mutations in this gene have been associated with skeletal ciliopathies, with or without polydactyly, such as such short-rib thoracic dysplasias 1, 9 or 10. [provided by RefSeq, Mar 2014] Function: Required for the maintenance and formation of cilia. Plays an indirect role in hedgehog (Hh) signaling, cilia being required for all activity of the hedgehog pathway. Subunit: Interacts with IFT88. Subcellular Location: Secreted. Similarity: Belongs to the IFT172 family. Contains 14 TPR repeats. Contains 9 WD repeats. SWISS: Q9UG01 Gene ID: 26160 Database links: Entrez Gene: 26160 Human Omim: 607386 Human SwissProt: Q9UG01 Human Unigene: 127401 Human |