| 產(chǎn)品編號(hào) | bs-15530R |
| 英文名稱 | Rabbit Anti-IBP160 antibody |
| 中文名稱 | 160kDa內(nèi)含子結(jié)合蛋白抗體 |
| 別 名 | AQR; AQR_HUMAN; aquarius; aquarius homolog (mouse); DKFZp686B23123; fSAP164; functional spliceosome-associated protein 164; IBP160; Intron-binding protein aquarius; Intron-binding protein of 160 kDa; KIAA0560. |
| 研究領(lǐng)域 | 染色質(zhì)和核信號(hào) 表觀遺傳學(xué) |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Sheep,Cow,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 171kDa |
| 細(xì)胞定位 | 細(xì)胞核 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human IBP160: 1-100/1485 |
| 亞 型 | |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre-mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing. Subunit: Identified in the spliceosome C complex. Subcellular Location: Nucleus. Note=Localizes to speckle-like regions of the nucleoplasm. Similarity: Belongs to the CWF11 family. SWISS: O60306 Gene ID: 9716 Database links: Entrez Gene: 9716 Human Omim: 610548 Human SwissProt: O60306 Human Unigene: 510958 Human |
