產(chǎn)品編號(hào) | bs-15373R |
英文名稱 | Rabbit Anti-GPR70 antibody |
中文名稱 | G蛋白偶聯(lián)受體TAS1R1蛋白抗體 |
別 名 | G protein coupled receptor 70; G protein-coupled receptor 70; G-protein coupled receptor 70; G-protein coupled receptor 70; gm 148; gm148;GPR 70; GPR70; Krueppel related zinc finger protein 3 (HKR3 protein); seven transmembrane helix receptor; Sweet taste receptor T1r; T1R1; TAS1 R1; TAS1R1; Taste receptor type 1 member 1; taste receptor, type 1, member 1; TR 1; TR1; TS1R1; TS1R1_HUMAN. |
研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 神經(jīng)生物學(xué) G蛋白偶聯(lián)受體 G蛋白信號(hào) |
抗體來(lái)源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human) |
產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 91kDa |
細(xì)胞定位 | 細(xì)胞膜 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human GPCR TAS1R1: 431-530/841 <Extracellular> |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
The protein encoded by this gene is a G protein-coupled receptor and is a component of the heterodimeric amino acid taste receptor T1R1+3. The T1R1+3 receptor responds to L-amino acids but not to D-enantiomers or other compounds. Most amino acids that are perceived as sweet activate T1R1+3, and this activation is strictly dependent on an intact T1R1+3 heterodimer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010] Function: Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate). Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses. Subunit: Forms heterodimers with TAS1R3. Subcellular Location: Cell membrane; Multi-pass membrane protein. Similarity: Belongs to the G-protein coupled receptor 3 family. TAS1R subfamily. SWISS: Q7RTX1 Gene ID: 80835 Database links: Entrez Gene: 80835 Human Entrez Gene: 110326 Mouse Omim: 606225 Human SwissProt: Q7RTX1 Human SwissProt: Q99PG6 Mouse Unigene: 124574 Human Unigene: 29232 Mouse Unigene: 92309 Rat |