| 產(chǎn)品編號(hào) | bs-15361R |
| 英文名稱 | Rabbit Anti-GPR62 antibody |
| 中文名稱 | G蛋白偶聯(lián)受體GPR62蛋白抗體 |
| 別 名 | GPCR GPR62; G-protein coupled receptor GPCR8; G-protein coupled receptor KPG_005; GPCR8; GPR62; hGPCR8; KPG_005; MGC26943; Probable G-protein coupled receptor 62; GPR62_HUMAN; GPCR 62. |
| 研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 神經(jīng)生物學(xué) 信號(hào)轉(zhuǎn)導(dǎo) G蛋白偶聯(lián)受體 G蛋白信號(hào) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Pig,Cow) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 38kDa |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human GPR62: 31-130/368 <Extracellular> |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
GPR62 is a 368 amino acid protein encoded by the human GPR62 gene. GPR62 is an orphan receptor member of the G protein-coupled receptor 1 family. G protein-coupled receptors (GPCRs or GPRs) contain seven transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. Key roles for G protein-coupled receptors include control of protein maturation and cell surface delivery and providing the correct framework for interactions with both heterotrimeric G proteins and arrestins to allow signal generation and its termination. GPR62 is expressed in brain tissue, most notably the basal forebrain, frontal cortex, caudate, putamen, thalamus and hippocampus. Function: Orphan receptor. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Expressed in brain; detected in the basal forebrain, frontal cortex, caudate, putamen, thalamus and hippocampus. Similarity: Belongs to the G-protein coupled receptor 1 family. SWISS: Q9BZJ7 Gene ID: 118442 Database links: Entrez Gene: 118442 Human Omim: 606917 Human SwissProt: Q9BZJ7 Human Unigene: 232213 Human |
