| 產(chǎn)品編號(hào) | bs-15354R |
| 英文名稱 | Rabbit Anti-GPR10 antibody |
| 中文名稱 | G蛋白偶聯(lián)受體GPR10蛋白抗體 |
| 別 名 | G-protein coupled receptor 10; GPCR 10; GPR10; GR3; hGR3; MGC126539; MGC126541; PRLHR; Prolactin-releasing peptide receptor; PrRP receptor; PrRPR; PRLHR_HUMAN. |
| 研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 神經(jīng)生物學(xué) 信號(hào)轉(zhuǎn)導(dǎo) G蛋白偶聯(lián)受體 G蛋白信號(hào) |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Cow) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 41kDa |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human GPR10 protein: 151-250/370 <Extracellular> |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
GPR10 acts as a receptor for prolactin-releasing peptide (PrRP). GPR10 plays a role in the regulation of food intake, pain-signal processing and lactation. Primarily expressed in pituitary gland, it is repressed by bromocriptine. GPR10 interacts with various other proteins, including GRIP1, GRIP2 and PICK1. Function: Receptor for prolactin-releasing peptide (PrRP). Implicated in lactation, regulation of food intake and pain-signal processing. Subunit: Interacts through its C-terminal region with the PDZ domain-containing proteins GRIP1, GRIP2 and PICK1. Interacts with PDZ domains 4 and 5 of GRIP1 and with the PDZ domain of PICK1. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Only detected in the pituitary gland and in all cell types of pituitary adenomas. Similarity: Belongs to the G-protein coupled receptor 1 family. SWISS: P49683 Gene ID: 2834 Database links: Entrez Gene: 2834 Human Entrez Gene: 226278 Mouse Omim: 600895 Human SwissProt: P49683 Human SwissProt: Q6VMN6 Mouse Unigene: 248119 Human Unigene: 377241 Mouse Unigene: 138127 Rat |
