| 產(chǎn)品編號 | bs-13457R |
| 英文名稱 | Rabbit Anti-GMFG antibody |
| 中文名稱 | 膠漿成熟因子γ/GMF-γ抗體 |
| 別 名 | Glia maturation factor gamma; Glia maturation factor, gamma; GMF GAMMA; GMF-gamma; Gmfg; GMFG_HUMAN; MGC126867. |
| 研究領(lǐng)域 | 細(xì)胞生物 轉(zhuǎn)運蛋白 細(xì)胞骨架 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 17kDa |
| 細(xì)胞定位 | 細(xì)胞外基質(zhì) |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human GMFG: 51-142/142 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
GMF-gamma is a 142 amino acid protein that belongs to the GMF subfamily of the larger actin-binding protein ADF family. GMF-gamma is expressed predominantly in lung, heart and placenta. GMF-gamma is considered a candidate regulatory growth factor protein, mediating both paracrine and autocrine cell-cell interactions. GMF-gamma is phosphorylated at N-terminal serine, and its phosphorylation is enhanced by coexpression of dominant active Rac 1 and Cdc42. GMF-gamma expression is significantly increased in a cardiac ischemia/reperfusion model where inflammation and angiogenesis take place actively. As a regulator of actin-based cellular functions, GMF-gamma may provide a novel approach to modulate the pathophysiology of cardiovascular diseases. GMF-gamma is primarily found in proliferative and differentiative organs. Tissue Specificity: Expressed predominantly in lung, heart and placenta. Similarity: Belongs to the actin-binding proteins ADF family. GMF subfamily. Contains 1 ADF-H domain. SWISS: O60234 Gene ID: 9535 Database links: Entrez Gene: 9535 Human Entrez Gene: 63986 Mouse Omim: 604104 Human SwissProt: O60234 Human SwissProt: Q9ERL7 Mouse Unigene: 5210 Human Unigene: 194536 Mouse |
