產(chǎn)品編號(hào) | bs-13192R |
英文名稱 | Rabbit Anti-FNDC4 antibody |
中文名稱 | Ⅲ型纖維連接蛋白域蛋白4抗體 |
別 名 | Fibronectin type III domain containing 4; Fibronectin type III domain containing protein 4; Fibronectin type III domain-containing protein 4; Fibronectin type III repeat containing protein 1; Fibronectin type III repeat-containing protein 1; FLJ22362; FNDC 4; FNDC4; FNDC4_HUMAN; FRCP 1; FRCP1. |
Specific References (2) | bs-13192R has been referenced in 2 publications.
[IF=4.452] Baolin Wang. et al. FNDC4 acts as an extracellular factor to promote the invasiveness of hepatocellular carcinoma partly via the PI3K/Akt signalling pathway. 2021 Aug 21 IHC ; Human.
[IF=3.694] Zhao Wang . et al. Fibronectin type III domain-containing 4 promotes the migration and differentiation of bovine skeletal muscle-derived satellite cells via focal adhesion kinase. Cell Adhes Migr. 2020;14(1):153-164 WB,IF,IP ; Bovine.
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研究領(lǐng)域 | 細(xì)胞生物 細(xì)胞粘附分子 細(xì)胞分化 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Dog) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 21kDa |
細(xì)胞定位 | 細(xì)胞膜 分泌型蛋白 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human FNDC4: 101-200/234 <Extracellular> |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
Fibronectins are multi-domain glycoproteins that bind to a variety of substances including collagen, actin, heparin, DNA, fibrin and fibronectin receptors. They are involved in a diverse array of important functions such as blood coagulation, wound healing, cell adhesion, cell differentiation and migration. FNDC4 (Fibronectin type III domain-containing protein 4), also known as FRCP1 (Fibronectin type III repeat-containing protein 1), is a 234 amino acid membrane protein that contains one fibronectin type-III domain, which serves as a binding site for DNA, heparin or the cell surface. The gene encoding FNDC4 is localized to human chromosome two, which houses over 1,400 genes and comprises nearly 8% of the human genome. Subcellular Location: Membrane; Single-pass type I membrane protein (Potential). Similarity: Contains 1 fibronectin type-III domain. SWISS: Q9H6D8 Gene ID: 64838 Database links: Entrez Gene: 64838 Human Entrez Gene: 64339 Mouse GenBank: NP_073734.1 Human Omim: 611905 Human SwissProt: Q9H6D8 Human SwissProt: Q3TR08 Mouse Unigene: 27836 Human Unigene: 732184 Human Unigene: 292544 Mouse |