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Rabbit Anti-ENOSF1  antibody (bs-13070R)  
~~~促銷代碼KT202411~~~
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說明書: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價
產(chǎn)品編號 bs-13070R
英文名稱 Rabbit Anti-ENOSF1  antibody
中文名稱 烯醇化酶超家族成員1抗體
別    名 Enolase superfamily member 1; ENOSF 1; HSRTSBETA; RTS alpha; RTS; RTS beta; RTS beta protein; TYMSAS;   
研究領域 腫瘤  細胞生物  信號轉(zhuǎn)導  新陳代謝  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Rabbit,Dog)
產(chǎn)品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 50kDa
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ENOSF1: 351-443/443 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The rTS gene codes for a naturally occurring antisense RNA to thymidylate synthase (TS) mRNA and two proteins (rTSalpha and rTSbeta (also known as ENOSF1)). The role of the major protein product of rTS, ENOSF1 has been linked to alterations in TS protein expression, but the precise function of ENOSF1 is unknown. Expression of rTS is associated with growth arrest in cell culture, but its overexpression has been noted in cells resistant to anticancer drugs such as 5-fluorouracil and methotrexate. Studies have shown that increased expression of ENOSF1 is associated with the decrease in TS protein expression due to production of novel, diffusible signal molecules.

Function:
May regulate thymidylate synthase activity.

Subcellular Location:
Mitochondrial.

Post-translational modifications:
Could be sumoylated.

Similarity:
Belongs to the mandelate racemase/muconate lactonizing enzyme family. ENOSF1 subfamily.

SWISS:
Q7L5Y1

Gene ID:
55556

Database links:

Entrez Gene: 615106 Cow

Entrez Gene: 480185 Dog

Entrez Gene: 100146163 Horse

Entrez Gene: 55556 Human

Entrez Gene: 100341613 Rabbit

SwissProt: Q7L5Y1 Human

Unigene: 658550 Human

Unigene: 731510 Human

Unigene: 732707 Human



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