| 產(chǎn)品編號(hào) | bs-13042R |
| 英文名稱 | Rabbit Anti-DMWD antibody |
| 中文名稱 | 強(qiáng)直性肌營(yíng)養(yǎng)不良相關(guān)蛋白9抗體 |
| 別 名 | dystrophia myotonica containing WD repeat motif; D19S593E; DM 9; DM9; DMR N9; DMR N9 protein; DMRN 9; DMRN9; DMWD; DMWD_HUMAN; Dystrophia myotonica containing WD repeat motif; Dystrophia myotonica containing WD repeat motif protein; Dystrophia myotonica WD repeat containing protein; Dystrophia myotonica WD repeat-containing protein; Dystrophia myotonica-containing WD repeat motif protein; Gene59; Protein 59; Protein DMR-N9. |
| 研究領(lǐng)域 | 細(xì)胞生物 神經(jīng)生物學(xué) |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Cow) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 70kDa |
| 細(xì)胞定位 | 細(xì)胞核 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human DMWD/DMRN9: 501-600/6754 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
DMWD is a 674 amino acid protein containing five WD repeats. DMWD may play a role in the development of mental symptoms in severe cases of myotonic dystrophy, a chronic multisystemic disease characterized by wasting of the muscles, heart conduction defects, cataracts, endocrine changes and myotonia. The DMWD gene is located upstream of the DMPK gene and is prominently expressed in tissues affected in myotonic dystrophy patients. DMWD may also contribute to regulation in meiosis. DMWD is expressed in kidney and spleen, with strongest expression in brain, liver and testis. The gene encoding DMWD maps to human chromosome 19q13.32 and mouse chromosome 7 A3. Function: Could have a regulatory function in meiosis. Subcellular Location: Contains 5 WD repeats. Tissue Specificity: Strongest expression in brain, liver, and testis. Also expressed in kidney and spleen. Similarity: Contains 5 WD repeats. SWISS: Q09019 Gene ID: 1762 Database links: Entrez Gene: 1762 Human Omim: 609857 Human SwissProt: Q09019 Human Unigene: 515474 Human |
