產(chǎn)品編號 | bs-12981R |
英文名稱 | Rabbit Anti-DAPL1 antibody |
中文名稱 | 凋亡相關(guān)蛋白激酶樣蛋白1抗體 |
別 名 | dapL1; DAPL1_HUMAN; death associated protein-like 1; Death-associated protein-like 1; Early epithelial differentiation-associated protein; EEDA; RP23-151F21.4. |
研究領(lǐng)域 | 細(xì)胞生物 細(xì)胞凋亡 激酶和磷酸酶 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Human (predicted: Mouse,Rat,Horse) |
產(chǎn)品應(yīng)用 | ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 12kDa |
細(xì)胞定位 | 細(xì)胞核 細(xì)胞漿 細(xì)胞膜 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human DAPL1: 1-100/107 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
In contrast to growth factors which promote cell proliferation, FAS ligand (FAS-L) and the tumor necrosis factors (TNFs) rapidly induce apoptosis. Cellular response to FAS-L and TNF is mediated by structurally related receptors containing a conserved cytoplasmic region called the “death domain”. DAPL1 (Death-associated protein-like 1), also known as EEDA (Early epithelial differentiation-associated protein), is a 107 amino acid protein that is expressed in hair follicles and is thought to function in a similar manner to DAP-1, possibly participating in the early stages of epithelial differentiation and/or apoptosis. Function: May play a role in the early stages of epithelial differentiation or in apoptosis. Tissue Specificity: Expressed in hair follicle (at protein level). SWISS: A0PJW8 Gene ID: 92196 Database links: Entrez Gene: 92196 Human Entrez Gene: 76747 Mouse SwissProt: A0PJW8 Human SwissProt: Q9D757 Mouse Unigene: 59761 Human Unigene: 275769 Mouse |