| 產(chǎn)品編號 | bs-12370R |
| 英文名稱 | Rabbit Anti-FAM65B antibody |
| 中文名稱 | FAM65B蛋白抗體 |
| 別 名 | Ab2 162; C6orf32; DIFF48; FA65B_HUMAN; Fam65b; KIAA0386; PL48; Protein FAM65B. |
| 研究領(lǐng)域 | 腫瘤 發(fā)育生物學(xué) 干細(xì)胞 糖尿病 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Mouse (predicted: Human,Rat,Rabbit,Pig,Sheep,Cow,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 118kDa |
| 細(xì)胞定位 | 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human FAM65B: 201-300/1068 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Making up nearly 6% of the human genome, chromosome 6 contains around 1,200 genes within 170 million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda is associated with chromosome 6 through the HFE gene which, when mutated, predisposes an individual to developing this porphyria. Notably, the PARK2 gene, which is associated with Parkinson's disease, and the genes encoding the major histocompatiblity complex proteins, which are key molecular components of the immune system and determine predisposition to rheumatic diseases, are also located on chromosome 6. Stickler syndrome, 21-hydroxylase deficiency and maple syrup urine disease are also associated with genes on chromosome 6. A bipolar disorder susceptibility locus has been identified on the q arm of chromosome 6. The C6orf32 gene product has been provisionally designated C6orf32 pending further characterization. Function: Isoform 2 play a role in promoting myogenic cell differentiation, cytoskeletal rearrangement and filopodia formation. Subcellular Location: Mitochondrion and Cytoplasm; cytoskeleton. Cell projection; filopodium. Detected in cellular filopodia. Tissue Specificity: Isoform 1 is present in the brain. Isoform 2 is expressed during differentiation of fetal primary myoblasts. Also shows marked expression during cytotrophoblast differentiation. Post-translational modifications: Asn-41 was reported (PubMed:16335952) to be N-glycosylated; however as this position is probably not extracellular, the in vivo relevance is not proven. Similarity: Belongs to the FAM65 family. SWISS: Q9Y4F9 Gene ID: 9750 Database links: Entrez Gene: 9750 Human SwissProt: Q9Y4F9 human |
| 產(chǎn)品圖片 |
Sample:
Bone (Mouse) Lysate at 40 ug
Primary: Anti- FAM65B (bs-12370R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 118 kD
Observed band size: 118 kD
Sample:
Thymus (Mouse) Lysate at 40 ug
Primary: Anti-FAM65B (bs-12370R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 118 kD
Observed band size: 118 kD
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