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Rabbit Anti-Calneuron 1  antibody (bs-12164R)  
~~~促銷代碼KT202411~~~
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說(shuō)明書: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-12164R
英文名稱 Rabbit Anti-Calneuron 1  antibody
中文名稱 鈣營(yíng)養(yǎng)蛋白1/鈣結(jié)合蛋白8抗體
別    名 CaBP8; CABP8_HUMAN; Calcium binding protein 8; Calcium binding protein; Calcium binding protein CABP8; Calcium-binding protein 8; Caln1; Calneuron I; Calneuron-1; Calneuron1.  
研究領(lǐng)域 細(xì)胞生物  神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  結(jié)合蛋白  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human,Mouse,Rat,Rabbit,Pig,Cow,Chicken,Dog,Horse)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 25kDa
細(xì)胞定位 細(xì)胞漿 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Calneuron 1/CABP8: 51-150/219 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes a protein with high similarity to the calcium-binding proteins of the calmodulin family. The encoded protein contains two EF-hand domains and potential calcium-binding sites. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008].

Function:
Negatively regulates Golgi-to-plasma membranetrafficking by interacting with PI4KB and inhibiting its activity(By similarity). May play a role in the physiology of neurons andis potentially important in memory and learning.

Subunit:
Interacts with PI4KB. This binding competes withFREQ/NCS1 binding in a calcium-dependent manner.

Subcellular Location:
Golgi apparatus, trans-Golgi network membrane. Cytoplasm, perinuclear region. Cell membrane.

Tissue Specificity:
Brain specific.

Similarity:
Contains 2 EF-hand domains.

SWISS:
Q9BXU9

Gene ID:
83698

Database links:

Entrez Gene: 83698 Human

Entrez Gene: 140904 Mouse

Entrez Gene: 363909 Rat

Omim: 607176 Human

SwissProt: Q9BXU9 Human

SwissProt: Q9JJG7 Mouse

SwissProt: Q06BI3 Rat

Unigene: 592750 Human

Unigene: 320206 Mouse

Unigene: 202895 Rat



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