| 產(chǎn)品編號 | bs-12147R |
| 英文名稱 | Rabbit Anti-ZIC5 antibody |
| 中文名稱 | 鋅指蛋白ZIC5抗體 |
| 別 名 | zic5; ZIC5_HUMAN; Zinc finger protein of the cerebellum 5; Zinc finger protein ZIC 5. |
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Specific References (2) | bs-12147R has been referenced in 2 publications.
[IF=7.109] Tan, Yi-Fan. et al. AR-regulated ZIC5 contributes to the aggressiveness of prostate cancer. CELL DEATH DISCOV. 2022 Sep;8(1):1-15 IHC, WB ; Human.
[IF=2.456] Han W et al. Clinicopathologic and Prognostic Significance of the Zinc Finger of the Cerebellum Family in Invasive Breast Cancer.J Breast Cancer. 2018 Mar;21(1):51-61. IHC ; Human.
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| 研究領(lǐng)域 | 細(xì)胞生物 神經(jīng)生物學(xué) 信號轉(zhuǎn)導(dǎo) 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Sheep,Cow,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 68kDa |
| 細(xì)胞定位 | 細(xì)胞核 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ZIC5: 501-600/663 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Zic5 (zinc finger protein of the cerebellum 5) is a C2H2 zinc finger transcription factor that influences development of the neural crest. Zic family members are abundant in
developing and adult cerebellum. Zic family members are important during development, and have been associated with X-linked visceral heterotaxy and holoprosencephaly type 5.
Zic5 is closely linked to Zic2, a related family member on chromosome 13. Function: Essential for neural crest development, converting cells from an epidermal fate to a neural crest cell fate. Binds to DNA. Subcellular Location: Nucleus. Similarity: Belongs to the GLI C2H2-type zinc-finger protein family. Contains 4 C2H2-type zinc fingers. SWISS: Q96T25 Gene ID: 85416 Database links: Entrez Gene: 85416 Human Entrez Gene: 65100 Mouse SwissProt: Q96T25 Human SwissProt: Q7TQ40 Mouse Unigene: 508570 Human Unigene: 390761 Mouse Unigene: 198356 Rat |
