產(chǎn)品編號(hào) | bs-12087R |
英文名稱 | Rabbit Anti-KCTD8 antibody |
中文名稱 | 鉀離子通道多聚體結(jié)構(gòu)域蛋白8抗體 |
別 名 | BTB/POZ domain-containing protein KCTD8; KCTD8; KCTD8_HUMAN; Potassium channel tetramerisation domain containing 8. |
研究領(lǐng)域 | 神經(jīng)生物學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 通道蛋白 細(xì)胞膜受體 G蛋白偶聯(lián)受體 G蛋白信號(hào) |
抗體來(lái)源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Mouse,Rat (predicted: Human,Rabbit,Pig,Sheep,Cow,Chicken,Dog,Horse) |
產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 52kDa |
細(xì)胞定位 | 細(xì)胞膜 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human KCTD8: 381-473/473 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization. Function: Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization (By similarity). Subunit: Interacts as a tetramer with GABRB1 and GABRB2 (By similarity). Subcellular Location: Cell junction > synapse > presynaptic cell membrane. Cell junction > synapse > postsynaptic cell membrane. Similarity: Contains 1 BTB (POZ) domain. SWISS: Q6ZWB6 Gene ID: 386617 Database links: Entrez Gene: 386617 Human Entrez Gene: 243043 Mouse SwissProt: Q6ZWB6 Human SwissProt: Q50H33 Mouse Unigene: 479644 Human Unigene: 234821 Mouse |
產(chǎn)品圖片 |
Sample:
Lane 1: Mouse Cerebrum tissue lysates
Lane 2: Mouse Cerebellum tissue lysates
Lane 3: Mouse Muscle tissue lysates
Lane 4: Rat Cerebrum tissue lysates
Lane 5: Rat Cerebellum tissue lysates
Lane 6: Rat Stomach tissue lysates
Lane 7: Rat Muscle tissue lysates
Primary: Anti-KCTD8 (bs-12087R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 52 kDa
Observed band size: 52 kDa
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