| 產(chǎn)品編號(hào) | bs-12032R |
| 英文名稱 | Rabbit Anti-GRASP antibody |
| 中文名稱 | 一般受體磷酸肌醇相關(guān)支架蛋白1抗體 |
| 別 名 | General Receptor for phosphoinositides 1; GRASP1; General receptor for phosphoinositides 1-associated scaffold protein; GRASP; GRASP_HUMAN; GRP1 (general receptor for phosphoinositides 1) associated scaffold protein; GRP1 associated scaffold protein; GRP1-associated scaffold protein; Tamalin. |
| 研究領(lǐng)域 | 神經(jīng)生物學(xué) 細(xì)胞膜受體 細(xì)胞骨架 |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Pig,Cow,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 45kDa |
| 細(xì)胞定位 | 細(xì)胞漿 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human GRASP: 156-260/395 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene encodes a protein that functions as a molecular scaffold, linking receptors, including group 1 metabotropic glutamate receptors, to neuronal proteins. The encoded protein contains conserved domains, including a leucine zipper sequence, PDZ domain and a C-terminal PDZ-binding motif. Alternately spliced transcript variants have been observed for this gene.[provided by RefSeq, Dec 2012] Function: Plays a role in intracellular trafficking and contributes to the macromolecular organization of group 1 metabotropic glutamate receptors (mGluRs) at synapses. Subunit: Heteromer. Composed of GRASP, PSCD2 and at least one GRM1. Also interacts with PSCD3, GRM2, GRM3 and GRM5 Subcellular Location: Cytoplasm, perinuclear region (By similarity). Cell membrane; Peripheral membrane protein; Cytoplasmic side (By similarity). Cell junction, synapse, postsynaptic cell membrane (By similarity). Note=Localized at postsynaptic membranes. Similarity: Contains 1 PDZ (DHR) domain. SWISS: Q7Z6J2 Gene ID: 160622 Database links: Entrez Gene: 160622 Human Entrez Gene: 56149 Mouse Omim: 612027 Human SwissProt: Q7Z6J2 Human SwissProt: Q9JJA9 Mouse Unigene: 407202 Human Unigene: 621295 Human Unigene: 276573 Mouse Unigene: 82758 Rat |
