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Rabbit Anti-GPR105  antibody (bs-12028R)  
~~~促銷代碼KT202411~~~
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說明書: 50ul  100ul  200ul
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產品編號 bs-12028R
英文名稱 Rabbit Anti-GPR105  antibody
中文名稱 G蛋白偶聯(lián)受體105抗體
別    名 A330108O13Rik; G protein coupled receptor for UDP-glucose; G protein-coupled receptor 105; G protein-coupled receptor VTR 15-20; G-protein coupled receptor 105; GPR105; KIAA0001; P2RY14; P2Y purinoceptor 14; P2Y(14) receptor; P2Y14; P2Y14 receptor; P2Y14_HUMAN; Purinergic receptor P2Y G protein coupled 14; Similar to TYPE-1 Angiotensin II receptor; UDP-glucose receptor; GPCR GPR105.  
研究領域 神經生物學  細胞膜受體  G蛋白偶聯(lián)受體  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse,Rat)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 39kDa
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human G-protein coupled receptor 105: 125-230/338 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 The product of this gene belongs to the family of G-protein coupled receptors, which contains several receptor subtypes with different pharmacological selectivity for various adenosine and uridine nucleotides. This receptor is a P2Y purinergic receptor for UDP-glucose and other UDP-sugars coupled to G-proteins. It has been implicated in extending the known immune system functions of P2Y receptors by participating in the regulation of the stem cell compartment, and it may also play a role in neuroimmune function. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]

Function:
Receptor for UDP-glucose and other UDP-sugar coupled to G-proteins. Not activated by ATP, ADP, UTP or ATP.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Tissue Specificity:
Highest expression in the placenta, adipose tissue, stomach and intestine, intermediate levels in the brain, spleen, lung and heart, lowest levels in the kidney.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

SWISS:
Q15391

Gene ID:
9934

Database links:

Entrez Gene: 9934 Human

Entrez Gene: 140795 Mouse

Entrez Gene: 171108 Rat

Omim: 610116 Human

SwissProt: Q15391 Human

SwissProt: Q9ESG6 Mouse

SwissProt: O35881 Rat

Unigene: 2465 Human

Unigene: 447969 Mouse

Unigene: 228423 Rat

Unigene: 87082 Rat



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