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Rabbit Anti-FLAD1  antibody (bs-11691R)  
~~~促銷代碼KT202411~~~
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說明書: 50ul  100ul  200ul
50ul/1180.00元
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200ul/2800.00元
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產(chǎn)品編號 bs-11691R
英文名稱 Rabbit Anti-FLAD1  antibody
中文名稱 黃素腺嘌呤二核苷酸抗體
別    名 FAD pyrophosphorylase; FAD synthetase; FAD synthetase region; FAD1; FAD1 flavin adenine dinucleotide synthetase homolog (S. cerevisiae); Fad1, flavin adenine dinucleotide synthetase, homolog; Fad1, flavin adenine dinucleotide synthetase, homolog (yeast); FADS; Flad1 protein; Flavin adenine dinucleotide synthetase; FMN adenylyl transferase; FMN adenylyltransferase; MGC187714; MGC31803; MGC40255; Molybdenum cofactor biosynthesis protein-like region; Pp591; RFad1, flavin adenine dinucleotide synthetase, homolog (yeast).  
研究領(lǐng)域 腫瘤  細(xì)胞生物  神經(jīng)生物學(xué)  信號轉(zhuǎn)導(dǎo)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human,Mouse,Rat,Cow,Zebrafish,Dog)
產(chǎn)品應(yīng)用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 65kDa
細(xì)胞定位 細(xì)胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FLAD1: 345-420/587 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 FLAD1 is a 587 amino acid protein where its N-terminus belongs to the moaB/mog family and its C-terminus belongs to the PAPS reductase family. Existing as five alternatively spliced isoforms, FLAD1 localizes to the cytoplasm and utilizes magnesium as a cofactor. FLAD1 is a key enzyme in the metabolic pathway that converts riboflavin into the redox cofactor flavin adenine dinucleotide (FAD). It is suggested that the molybdenum cofactor biosynthesis protein-like region of FLAD1 may not be functional.

Function:
FLAD1 catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Subcellular Location:
Cytoplasmic

Similarity:
In the N-terminal section; belongs to the MoaB/Mog family.
In the C-terminal section; belongs to the PAPS reductase family. FAD1 subfamily.

SWISS:
Q8NFF5

Gene ID:
80308

Database links:

Entrez Gene: 80308 Human

Entrez Gene: 319945 Mouse

Entrez Gene: 751787 Rat

Omim: 610595 Human

SwissProt: Q8NFF5 Human

SwissProt: Q8R123 Mouse

SwissProt: B1WBY2 Rat



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