產(chǎn)品編號 | bs-11691R |
英文名稱 | Rabbit Anti-FLAD1 antibody |
中文名稱 | 黃素腺嘌呤二核苷酸抗體 |
別 名 | FAD pyrophosphorylase; FAD synthetase; FAD synthetase region; FAD1; FAD1 flavin adenine dinucleotide synthetase homolog (S. cerevisiae); Fad1, flavin adenine dinucleotide synthetase, homolog; Fad1, flavin adenine dinucleotide synthetase, homolog (yeast); FADS; Flad1 protein; Flavin adenine dinucleotide synthetase; FMN adenylyl transferase; FMN adenylyltransferase; MGC187714; MGC31803; MGC40255; Molybdenum cofactor biosynthesis protein-like region; Pp591; RFad1, flavin adenine dinucleotide synthetase, homolog (yeast). |
研究領(lǐng)域 | 腫瘤 細(xì)胞生物 神經(jīng)生物學(xué) 信號轉(zhuǎn)導(dǎo) |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human,Mouse,Rat,Cow,Zebrafish,Dog) |
產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 65kDa |
細(xì)胞定位 | 細(xì)胞漿 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human FLAD1: 345-420/587 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
FLAD1 is a 587 amino acid protein where its N-terminus belongs to the moaB/mog family and its C-terminus belongs to the PAPS reductase family. Existing as five alternatively spliced isoforms, FLAD1 localizes to the cytoplasm and utilizes magnesium as a cofactor. FLAD1 is a key enzyme in the metabolic pathway that converts riboflavin into the redox cofactor flavin adenine dinucleotide (FAD). It is suggested that the molybdenum cofactor biosynthesis protein-like region of FLAD1 may not be functional. Function: FLAD1 catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme. Alternatively spliced transcript variants encoding distinct isoforms have been observed. Subcellular Location: Cytoplasmic Similarity: In the N-terminal section; belongs to the MoaB/Mog family. In the C-terminal section; belongs to the PAPS reductase family. FAD1 subfamily. SWISS: Q8NFF5 Gene ID: 80308 Database links: Entrez Gene: 80308 Human Entrez Gene: 319945 Mouse Omim: 610595 Human SwissProt: Q8NFF5 Human SwissProt: Q8R123 Mouse |