產(chǎn)品編號(hào) | bs-11672R |
英文名稱 | Rabbit Anti-Saitohin antibody |
中文名稱 | Saitohin蛋白抗體 |
別 名 | MAPTIT; Saitohin; STH; STH_HUMAN. |
研究領(lǐng)域 | 細(xì)胞生物 神經(jīng)生物學(xué) Alzheimer's |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 14kDa |
細(xì)胞定位 | 細(xì)胞核 細(xì)胞漿 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human STH/Saitohin: 51-128/128 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
The intronless STH gene lies between exons 9 and 10 of the tau gene, which is implicated in a number of neurodegenerative disorders. It encodes a 128 residue protein with no clear homologs, and mimics the expresison patterns of tau. Though a polymorphism (Q7R) appears significant, data does not clearly show thus far whether or not this phenotype provides a useful marker for Alzheimer’s or other forms of neurodegenerative disease. Function: Highest expression in placenta, muscle, fetal brain, and adult brain, with lower expression in heart, kidney, stomach, testis, and adrenal gland. In the central nervous system, highest expression is in temporal lobe, hypothalamus, medulla and spinal cord, with lower expression in other brain regions. Subcellular Location: Cytoplasm. Nucleus. Tissue Specificity: Highest expression in placenta, muscle, fetal brain, and adult brain, with lower expression in heart, kidney, stomach, testis, and adrenal gland. In the central nervous system, highest expression is in temporal lobe, hypothalamus, medulla and spinal cord, with lower expression in other brain regions. SWISS: Q8IWL8 Gene ID: 246744 Database links: Entrez Gene: 246744 Human Omim: 607067 Human SwissProt: Q8IWL8 Human Unigene: 661831 Human |