| 產(chǎn)品編號(hào) | bs-11650R |
| 英文名稱(chēng) | Rabbit Anti-ALS2CR3 antibody |
| 中文名稱(chēng) | 肌萎縮側(cè)索硬化癥相關(guān)蛋白3抗體 |
| 別 名 | ALS2CR3; Amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 3; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 protein;TRAK2_HUMAN; Trafficking kinesin-binding protein 2. |
| 研究領(lǐng)域 | 細(xì)胞生物 神經(jīng)生物學(xué) Alzheimer's |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 交叉反應(yīng) | Mouse (predicted: Human,Rat,Pig,Sheep,Cow,Dog) |
| 產(chǎn)品應(yīng)用 | ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 101kDa |
| 細(xì)胞定位 | 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ALS2CR3: 701-800/914 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
ALS2CR3 may regulate endosome-to-lysosome trafficking of membrane cargo, including EGFR. Function: May regulate endosome-to-lysosome trafficking of membrane cargo, including EGFR Subunit: Interacts with GABA-A receptor and O-GlcNAc transferase. Interacts with HGS (By similarity). Interacts with RHOT1/Miro-1 and RHOT2/Miro-2. Subcellular Location: Cytoplasm (By similarity). Early endosome (By similarity). Mitochondrion (By similarity). Note=Colocalizes with MGARP at the mitochondria. Translocates from the cytoplasm to the mitochondria in a MGARP-dependent manner Tissue Specificity: Widely expressed, with highest expression in heart. Post-translational modifications: O-glycosylated Similarity: Contains 1 HAP1 N-terminal domain. SWISS: O60296 Gene ID: 66008 Database links: Entrez Gene: 66008 Human Entrez Gene: 70827 Mouse Omim: 607334 Human SwissProt: O60296 Human Unigene: 152774 Human Unigene: 222887 Mouse |
