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Rabbit Anti-NPTX1  antibody (bs-4893R)  
~~~促銷代碼KT202411~~~
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產品編號 bs-4893R
英文名稱 Rabbit Anti-NPTX1  antibody
中文名稱 神經細胞正五聚體1抗體
別    名 Neuronal pentraxin I; Neuronal pentraxin-1; NP 1; NP-I; NP1; Nptx1; NPTX1_HUMAN.   
Specific References  (1)     |     bs-4893R has been referenced in 1 publications.
[IF=2.967] Jing Wu. et al. NPTX1 inhibits pancreatic cancer cell proliferation and migration and enhances chemotherapy sensitivity by targeting RBM10. Oncol Lett. 2022 May;23(5):1-9  WB ;  Human.  
研究領域 免疫學  神經生物學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse,Rat (predicted: Human,Rabbit,Pig,Cow,Chicken,Dog,Horse)
產品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 45kDa
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NPTX1: 201-300/432 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 NPTX1 is a member of the neuronal pentraxin gene family. Neuronal pentraxin 1 is similar to the rat NP1 gene which encodes a binding protein for the snake venom toxin taipoxin. Human NPTX1 mRNA is exclusively localized to the nervous system.

Function:
May mediate uptake of degraded synaptic material which could play an important role in synaptic remodeling. Can mediate the neuronal and glial uptake of the snake venom toxin taipoxin.

Subcellular Location:
Cytoplasmic vesicle, secretory vesicle (Potential).

Similarity:
Contains 1 pentaxin domain.

SWISS:
Q15818

Gene ID:
4884

Database links:

Entrez Gene: 4884 Human

Entrez Gene: 18164 Mouse

Entrez Gene: 266777 Rat

Omim: 602367 Human

SwissProt: Q15818 Human

SwissProt: Q62443 Mouse

SwissProt: P47971 Rat

Unigene: 514556 Human

Unigene: 719680 Human

Unigene: 5142 Mouse

Unigene: 54707 Rat



產品圖片
Sample: Lane 1: Mouse Cerebellum tissue lysates Lane 2: Mouse Liver tissue lysates Lane 3: Rat Cerebrum tissue lysates Lane 4: Rat Cerebellum tissue lysates Primary: Anti-NPTX1 (bs-4893R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 45 kDa Observed band size: 52 kDa
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