| 產(chǎn)品編號(hào) | bs-11171R |
| 英文名稱 | Rabbit Anti-NXPH2 antibody |
| 中文名稱 | 神經(jīng)外營(yíng)養(yǎng)蛋白2抗體 |
| 別 名 | Neurexophilin2; Neurexophilin 2; Neurexophilin-2; NPH2; Nxph2; Nxph-2; NXPH2_HUMAN; MGC125479; MGC125477; MGC125478; MGC125480. |
| 研究領(lǐng)域 | 神經(jīng)生物學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 細(xì)胞粘附分子 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Chicken,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 27kDa |
| 細(xì)胞定位 | 分泌型蛋白 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human NXPH2: 151-250/264 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Neurexophilin family (Neurexophilin-1-4) of neuropeptide-like glycoproteins that are proteolytically processed after synthesis. Neurexophilin-1-3 are secreted proteins that are thought to function as signaling molecules which specifically bind to target proteins, such as neurexin I?(a protein that promotes adhesion between dendrites and axons), and are essential for proper neurotransmitter release. While Neurexophilin-1 is located primarily in spleen tissue, Neurexophilin-2 is expressed primarily in kidney and both Neurexophilin-2 and Neurexophilin-3 are highly expressed in brain. Defects in the gene encoding Neurexophilin-1 may be associated with schizophrenia, a mental disorder characterized by an abnormal perception of reality. Function: May be signaling molecules that resemble neuropeptides and that act by binding to alpha-neurexins and possibly other receptors. Subunit: Belongs to the neurexophilin family. Subcellular Location: Secreted. Tissue Specificity: Expressed in brain and kidney. Post-translational modifications: May be proteolytically processed at the boundary between the N-terminal non-conserved and the central conserved domain in neuron-like cells (By similarity). Similarity: Belongs to the neurexophilin family. SWISS: O95156 Gene ID: 11249 Database links: Entrez Gene: 11249 Human Entrez Gene: 18232 Mouse Omim: 604635 Human SwissProt: O95156 Human SwissProt: Q61199 Mouse |
