| 產(chǎn)品編號 | bs-9903R |
| 英文名稱 | Rabbit Anti-SCUBE1 antibody |
| 中文名稱 | 新型血小板相關(guān)血管內(nèi)皮分泌蛋白SCUBE1抗體 |
| 別 名 | SCUB1_HUMAN; SCUBE 1; SCUBE1; Signal peptide, CUB and EGF-like domain-containing protein 1. |
| 研究領(lǐng)域 | 心血管 內(nèi)皮細(xì)胞 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Pig,Cow,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:50-200,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 105kDa |
| 細(xì)胞定位 | 細(xì)胞膜 分泌型蛋白 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SCUBE1: 451-550/988 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Could function as an adhesive molecule and its matrix bound and soluble fragments may play a critical role in vascular biology. Function: Could function as an adhesive molecule and its matrix bound and soluble fragments may play a critical role in vascular biology. Subunit: Forms homooligomers and heterooligomers with SCUBE2 and SCUBE3. Subcellular Location: Secreted. Cell membrane. Tissue Specificity: Detected in endothelial cells. Highly expressed in platelets. Stored in platelet alpha granules, and transferrred to the cell surface upon activation and aggregation. A smaller form, probably produced by limited proteolysis, after being released from the storage granules, is associated with thrombus and localized with the subendothelial matrices in atherosclerotic plaques. Post-translational modifications: N-glycosylated. Could be proteolytically cleaved to release a smaller active fragment. Similarity: Contains 1 CUB domain. Contains 9 EGF-like domains. SWISS: Q8IWY4 Gene ID: 80274 Database links: Entrez Gene: 80274 Human Entrez Gene: 64706 Mouse Omim: 611746 Human SwissProt: Q8IWY4 Human SwissProt: Q6NZL8 Mouse Unigene: 133995 Human Unigene: 40393 Mouse |
