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Rabbit Anti-PSMA5  antibody (bs-9354R)  
~~~促銷代碼KT202411~~~
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產(chǎn)品編號 bs-9354R
英文名稱 Rabbit Anti-PSMA5  antibody
中文名稱 蛋白酶體PSMα5抗體
別    名 Macropain zeta chain; Multicatalytic endopeptidase complex zeta chain; Proteasome (prosome macropain) subunit alpha type 5; Proteasome alpha5 subunit; Proteasome component 5; Proteasome subunit alpha type 5; Proteasome subunit alpha type-5; Proteasome subunit zeta; Proteasome zeta chain; PSA5_HUMAN; PSC5; ZETA; Proteasome 20S alpha 5.  
研究領(lǐng)域 細(xì)胞生物  細(xì)胞周期蛋白  細(xì)胞分化  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse,Rat (predicted: Human,Rabbit,Pig,Cow,Chicken)
產(chǎn)品應(yīng)用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:50-200,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 26.5kDa
細(xì)胞定位 細(xì)胞核 細(xì)胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PSMA5: 31-130/241 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.

Function:
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.

Subunit:
The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel. PSMA5 interacts directly with the PSMG1-PSMG2 heterodimer which promotes 20S proteasome assembly.

Subcellular Location:
Cytoplasm. Nucleus.

Tissue Specificity:
Expressed in fetal brain (at protein level).

Similarity:
Belongs to the peptidase T1A family.

SWISS:
P28066

Gene ID:
5686

Database links:

Entrez Gene: 5686 Human

Entrez Gene: 26442 Mouse

Entrez Gene: 29672 Rat

Omim: 176844 Human

SwissProt: P28066 Human

SwissProt: Q9Z2U1 Mouse

SwissProt: P34064 Rat

Unigene: 485246 Human

Unigene: 208883 Mouse

Unigene: 1276 Rat



產(chǎn)品圖片
Sample: Lane 1: Thymus (Mouse) Tissue Lysate at 40 ug Lane 2: NIH/3T3 (Mouse) Cell Lysate at 30 ug Lane 3: Liver (Rat) Tissue Lysate at 40 ug Lane 4: Thymus (Rat) Tissue Lysate at 40 ug Primary: Anti-PSMA5 (bs-9354R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 26.5 kD Observed band size: 27 kD
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