| 產(chǎn)品編號(hào) | bs-9069R |
| 英文名稱(chēng) | Rabbit Anti-HN1 antibody |
| 中文名稱(chēng) | 雄激素調(diào)節(jié)蛋白2抗體 |
| 別 名 | Androgen regulated protein 2; Androgen-regulated protein 2; ARM2; Hematological and neurological expressed 1; Hematological and neurological expressed 1 protein; HN1; HN1_HUMAN; HN1A. |
| 研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 激酶和磷酸酶 |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:50-200,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 16kDa |
| 細(xì)胞定位 | 細(xì)胞核 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human HN1/ARM2: 21-100/154 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Hematological and neurological expressed 1 protein (HN1) is a 154 amino acid member of the HN1 family. HN1 has been proposed to play a role in embryo development, specifically hemopoietic cell and neurological development. Localized to the nucleus, HN1 is expressed in many fetal and adult tissues, with highest levels of expression in brain, colon, prostate, testis, thymus, skeletal muscle, peripheral blood cells and placenta. HN1 has been identified to have processed pseudogenes in the mouse, rat and human genomes, suggesting that HN1 and its pseudogenes represent a novel gene family. Three isoforms of HN1 exist as a result of alternative splicing events. HN1L (hematological and neurological expressed 1-like protein), also known as C16orf34 or L11, is a 190 amino acid protein that belongs to the HN1 family. Localizing to the cytoplasm as well as the nucleus, HN1L is expressed in liver, kidney, prostate, testis and uterus. HN1L gets upregulated in certain carcinomas, including squamous cell carcinoma (SCC), adenocarcinoma (AC), adenosquamous cell carcinoma (ASCC) and bronchioalveolar carcinoma (BAC), and is also expressed in breast and uterine tumors. HN1L, along with HN1, may be involved in embryo development. Subcellular Location: Nucleus Tissue Specificity: Expressed in testis, skeletal muscle, thymus, prostate, colon, peripheral blood cells, brain and placenta. Post-translational modifications: Isoform 3 initiator methionine is either acetylated or removed. In the latter case, the new N-terminal amino acid is then N-acetylated. Similarity: Belongs to the HN1 family. SWISS: Q9UK76 Gene ID: 51155 Database links: Entrez Gene: 51155 Human Entrez Gene: 15374 Mouse SwissProt: Q9UK76 Human SwissProt: P97825 Mouse Unigene: 532803 Human Unigene: 1775 Mouse Unigene: 198910 Rat |
