產(chǎn)品編號(hào) | bs-9028R |
英文名稱 | Rabbit Anti-AKAP2/PALM2 antibody |
中文名稱 | 蛋白激酶A2抗體 |
別 名 | A kinase (PRKA) anchor protein 2; A kinase anchor protein 2; AKAP 2; AKAP KL; AKAPKL; KIAA0920; PALM 2; PALM2; PRKA 2; PRKA2; Protein kinase A anchoring protein 2; Protein kinase A2; AKAP2_HUMAN. |
Specific References (1) | bs-9028R has been referenced in 1 publications.
[IF=4.147] Bing Wang. et al. AKAP2 overexpression modulates growth plate chondrocyte functions through ERK1/2 signaling. Bone. 2021 May;146:115875 WB,IF ; Human.
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研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 激酶和磷酸酶 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Human (predicted: Mouse,Rabbit,Pig,Sheep,Cow,Chicken,Horse) |
產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:50-200,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 95kDa |
細(xì)胞定位 | 細(xì)胞漿 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human AKAP2: 151-250/859 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
AKAP2 binds to regulatory subunit (RII) of protein kinase A and can be differentially expressed as a natural AKAP2-PALM2 chimeric protein. It may be involved in establishing polarity in signaling systems or in integrating PKA-RII isoforms with downstream effectors to capture, amplify and focus diffuse, trans-cellular signals carried by cAMP. There are 2 named isoforms produced by alternative splicing. Function: Binds to regulatory subunit (RII) of protein kinase A. May be involved in establishing polarity in signaling systems or in integrating PKA-RII isoforms with downstream effectors to capture, amplify and focus diffuse, trans-cellular signals carried by cAMP (By similarity). SWISS: Q9Y2D5 Gene ID: 11217 Database links: Entrez Gene: 11217 Human Omim: 604582 Human SwissProt: Q9Y2D5 Human |