| 產(chǎn)品編號 | bs-8164R |
| 英文名稱 | Rabbit Anti-TBL1Y antibody |
| 中文名稱 | 轉(zhuǎn)導(dǎo)β樣蛋白1抗體 |
| 別 名 | Y-linked; F-box-like/WD repeat-containing protein TBL1Y; TBL1; TBL1Y; TBL1Y_HUMAN; Transducin (beta) like 1, Y linked; Transducin beta-like 1; Transducin beta-like protein 1Y; Transducin-beta-like protein 1; Transducin-beta-like protein 1, Y-linked. |
| 研究領(lǐng)域 | 腫瘤 細胞生物 免疫學(xué) 染色質(zhì)和核信號 信號轉(zhuǎn)導(dǎo) 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Pig,Cow,Chicken,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 57kDa |
| 細胞定位 | 細胞核 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human TBL1Y: 351-450/522 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
FunctionF-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of corepressor complexes that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of transcription repressor complexes, thereby allowing cofactor exchange. Function: F-box-like protein involved in the recruitment of theubiquitin/19S proteasome complex to nuclear receptor-regulatedtranscription units. Plays an essential role in transcriptionactivation mediated by nuclear receptors. Probably acts as integralcomponent of corepressor complexes that mediates the recruitment ofthe 19S proteasome complex, leading to the subsequent proteasomaldegradation of transcription repressor complexes, thereby allowingcofactor exchange (By similarity). Subunit: Probable component of the N-Cor repressor complex andsome E3 ubiquitin ligase complex (By similarity). Subcellular Location: Nucleus (By similarity). Tissue Specificity: Fetal brain and prostate. Similarity: Belongs to the WD repeat EBI family. Contains 1 F-box-like domain. Contains 1 LisH domain. Contains 8 WD repeats. SWISS: Q9BQ87 Gene ID: 90665 Database links:
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