| 產(chǎn)品編號(hào) | bs-8044R |
| 英文名稱 | Rabbit Anti-KBTBD10 antibody |
| 中文名稱 | BTB-kelch蛋白家族10抗體 |
| 別 名 | cb52; fb24f05; fc15e07; Gm112; KBTBD10; Kel like protein 23; Kelch related protein 1; KRP1; MGC143407; Sarcosin; sbcb52; wufb24f05; wufc15e07; KBTBA_HUMAN. |
| 研究領(lǐng)域 | 心血管 細(xì)胞生物 發(fā)育生物學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 細(xì)胞凋亡 轉(zhuǎn)錄調(diào)節(jié)因子 細(xì)胞骨架 |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 交叉反應(yīng) | Mouse (predicted: Human,Rat,Rabbit,Pig,Sheep,Cow,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 68kDa |
| 細(xì)胞定位 | 細(xì)胞漿 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human KBTBD10: 542-606/606 |
| 亞 型 | |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Sarcosin contains 1 BTB (POZ) domain and is required for pseudopod elongation in transformed cells. Sarcosin mRNA is up-regulated by less than two folds in the heart in human patients with HCM. Function: Required for pseudopod elongation in transformed cells. Substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Subunit: Interacts with NRAP (By similarity). Part of a complex that contains CUL3, RBX1 and KBTBD10. Subcellular Location: Cytoplasm. Cytoplasm, cytoskeleton. Cell projection, pseudopodium. Cell projection, ruffle. Note=Predominantly cytoplasmic but can co-localize with F-actin at the membrane ruffle-like structures at the tips of transformation-specific pseudopodia. Post-translational modifications: Ubiquitinated and probably targeted for proteasome-independent degradation. Similarity: Contains 1 BTB (POZ) domain. Contains 5 Kelch repeats. SWISS: O60662 Gene ID: 10324 Database links: Entrez Gene: 10324 Human Entrez Gene: 228003 Mouse SwissProt: O60662 Human SwissProt: A2AUC9 Mouse Unigene: 50550 Human
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| 產(chǎn)品圖片 |
Sample:
Spinal cord (Mouse) Lysate at 40 ug
Primary: Anti- KBTBD10 (bs-8044R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 68 kD
Observed band size: 68 kD
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