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Rabbit Anti-SIK2  antibody (bs-6930R)  
~~~促銷代碼KT202411~~~
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產品編號 bs-6930R
英文名稱 Rabbit Anti-SIK2  antibody
中文名稱 絲氨酸/蘇氨酸蛋白激酶SIK2抗體
別    名 QIK; Qin induced kinase; Qin-induced kinase; Salt inducible kinase 2; Salt inducible protein kinase 2; Salt inducible serine/threonine kinase 2; Salt-inducible protein kinase 2; Serine/threonine protein kinase SIK2; Serine/threonine protein kinase SNF1 like kinase 2; Serine/threonine-protein kinase SIK2; Serine/threonine-protein kinase SNF1-like kinase 2; SIK 2; SIK-2; ; SIK2_HUMAN; SNF1 like kinase; SNF1 like kinase 2; SNF1LK2; DKFZp434K1115; EC 2.7.11.1; KIAA0781; LOH11CR1I.  
Specific References  (1)     |     bs-6930R has been referenced in 1 publications.
[IF=2.248] Wei Shunying. et al. Overexpression of circ_CELSR1 facilitates paclitaxel resistance of ovarian cancer by regulating miR-149-5p/SIK2 axis. Anti-Cancer Drug. 2021 Jun;32(5):496-507  WB ;  Human.  
研究領域 腫瘤  細胞生物  神經(jīng)生物學  信號轉導  激酶和磷酸酶  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human (predicted: Mouse)
產品應用 WB=1:500-2000,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 104kDa
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SNF1LK2/SIK2: 281-380/926 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Phosphorylates 'Ser-794' of IRS1 in insulin-stimulated adipocytes, potentially modulating the efficiency of insulin signal transduction. Inhibits CREB activity by phosphorylating and repressing TORCs, the CREB-specific coactivators.

Subunit:
Interacts with and phosphorylates TORC2/CRTC2.

Subcellular Location:
Cytoplasm

Similarity:
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
Contains 1 protein kinase domain.
Contains 1 UBA domain.

SWISS:
Q9H0K1

Gene ID:
23235

Database links:

Entrez Gene: 23235 Human

Entrez Gene: 235344 Mouse

Entrez Gene: 315649 Rat

Omim: 608973 Human

SwissProt: Q9H0K1 Human

SwissProt: Q8CFH6 Mouse

Unigene: 269128 Human

Unigene: 104932 Mouse



產品圖片
Sample: Lane 1: Human SH-SY5Y cell lysates Lane 2: Human U251 cell lysates Lane 3: Human HepG2 cell lysates Lane 4: Human Jurkat cell lysates Lane 5: Human A431 cell lysates Primary: Anti-SIK2 (bs-6930R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 104 kDa Observed band size: 100 kDa
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