產(chǎn)品編號(hào) | bs-7823R |
英文名稱(chēng) | Rabbit Anti-DNA polymerase subunit II antibody |
中文名稱(chēng) | DNA聚合酶α2抗體 |
別 名 | DNA directed DNA polymerase alpha 2; DNA polymerase alpha 70 kDa subunit; DNA polymerase alpha subunit II; DNA polymerase subunit alpha B; DNA polymerase subunit II; FLJ21662; FLJ37250; Polymerase (DNA directed), alpha (70kD); DPOA2_HUMAN. |
研究領(lǐng)域 | 細(xì)胞生物 細(xì)胞周期蛋白 細(xì)胞分化 表觀遺傳學(xué) |
抗體來(lái)源 | Rabbit |
克隆類(lèi)型 | Polyclonal |
交叉反應(yīng) | (predicted: Human,Mouse,Rat,Sheep,Cow,Horse) |
產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 66kDa |
細(xì)胞定位 | 細(xì)胞核 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human POLA2: 201-300/598 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
May play an essential role at the early stage of chromosomal DNA replication by coupling the polymerase alpha/primase complex to the cellular replication machinery. Function: May play an essential role at the early stage ofchromosomal DNA replication by coupling the polymerasealpha/primase complex to the cellular replication machinery (Bysimilarity). Subunit: DNA polymerase alpha:primase is a four subunit enzymecomplex, which is assembled throughout the cell cycle, and consistsof the two DNA polymerase subunits A and B, and the DNA primaselarge and small subunits. Subunit B binds to subunit A. Subcellular Location: Nucleus. Post-translational modifications: Phosphorylated in a cell cycle-dependent manner, in G2/M phase. Similarity: Belongs to the DNA polymerase alpha subunit B family. SWISS: Q14181 Gene ID: 23649 Database links: Entrez Gene: 23649 Human SwissProt: Q14181 Human Unigene: 201897 Human |