產(chǎn)品編號(hào) | bs-7748R |
英文名稱 | Rabbit Anti-FMN2 antibody |
中文名稱 | 形成素2抗體(成蛋白) |
別 名 | FMN 2; FMN-2; Formin2; Formin-2; Formin 2. |
研究領(lǐng)域 | 細(xì)胞生物 神經(jīng)生物學(xué) 細(xì)胞周期蛋白 細(xì)胞骨架 細(xì)胞外基質(zhì) |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Rat (predicted: Human,Mouse,Rabbit,Cow,Chicken,Dog) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 189kDa |
細(xì)胞定位 | 細(xì)胞核 細(xì)胞漿 細(xì)胞膜 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human FMN2: 401-500/1722 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
FMN2 is a member or the formin homology family, Cappuccino subfamily. Formin homology (FH) domain proteins play a role in cytoskeletal organization and/or establishment of cell polarity. In mice, FMN2 has been shown to be a maternal effect gene that is expressed in oocytes and is required for progression through metaphase of meiosis I. FMN2 is expressed in the developing and mature central nervous system. Subcellular Location: Expressed almost exclusively in the developing and mature central nervous system. Post-translational modifications: Phosphorylated upon DNA damage, probably by ATM or ATR. Similarity: Belongs to the formin homology family. Cappuccino subfamily. Contains 1 FH1 (formin homology 1) domain. Contains 1 FH2 (formin homology 2) domain. SWISS: Q9NZ56 Gene ID: 56776 |
產(chǎn)品圖片 |
Tissue/cell: rat brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
Incubation: Anti-FMN2 Polyclonal Antibody, Unconjugated(bs-7748R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
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