產品編號 | bs-6394R |
英文名稱 | Rabbit Anti-QSOX1 antibody |
中文名稱 | 巰基氧化酶1抗體 |
別 名 | QSOX1_HUMAN; Sulfhydryl oxidase 1; QSCN6; EC:1.8.3.2; hQSOX; Quiescin Q6; UNQ2520/PRO6013; quiescin sulfhydryl oxidase 1; Q6; |
研究領域 | 腫瘤 細胞生物 細胞周期蛋白 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應 | (predicted: Human,Mouse,Rat,Rabbit,Cow,Dog,Horse) |
產品應用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 80kDa |
細胞定位 | 細胞漿 細胞膜 細胞外基質 分泌型蛋白 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human QSOX1: 244-350/747 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產品介紹 |
This gene encodes a protein that contains domains of thioredoxin and ERV1, members of two long-standing gene families. The gene expression is induced as fibroblasts begin to exit the proliferative cycle and enter quiescence, suggesting that this gene plays an important role in growth regulation. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Function: Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide. May contribute to disulfide bond formation in a variety of secreted proteins. In fibroblasts, it may have tumor-suppressing capabilities being involved in growth regulation. Subunit: Monomer. Subcellular Location: Isoform 1: Golgi apparatus membrane; Single-pass membrane protein. Isoform 2: Secreted, extracellular space. Note=Found in the extracellular medium of quiescent cells but is not found in proliferating cells. Similarity: Belongs to the quiescin-sulfhydryl oxidase (QSOX) family. Contains 1 ERV/ALR sulfhydryl oxidase domain. Contains 1 thioredoxin domain. SWISS: O00391 Gene ID: 5768 Database links: Entrez Gene: 5768 Human Entrez Gene: 104009 Mouse Omim: 603120 Human SwissProt: O00391 Human SwissProt: Q8BND5 Mouse Unigene: 518374 Human Unigene: 719176 Human Unigene: 27035 Mouse Unigene: 44920 Rat |
1、抗體溶解方法 | |
2、抗體修復方式 | |
3、常用試劑的配制 | |
4、免疫組化操作步驟 | |
5、免疫組化問題解答 | |
6、Western Blotting 操作步驟 | |
7、Western Blotting 問題解答 | |
8、關于肽鏈的設計 | |
9、多肽的溶解與保存 | |
10、酶標抗體效價測定程序 | |