| 產(chǎn)品編號(hào) | bs-6376R |
| 英文名稱 | Rabbit Anti-DDIT4L antibody |
| 中文名稱 | DNA損傷誘導(dǎo)轉(zhuǎn)錄樣蛋白4抗體 |
| 別 名 | DNA damage inducible transcript 4 like protein; HIF 1 responsive protein RTP801 like; Homolog of mouse SMHS1; Protein regulated in development and DNA damage response 2; REDD 2; REDD2; RTP801L; DDT4L_HUMAN. |
| 研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 細(xì)胞周期蛋白 轉(zhuǎn)錄調(diào)節(jié)因子 |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human,Mouse (predicted: Rat,Rabbit,Pig,Cow,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 22kDa |
| 細(xì)胞定位 | 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human DDIT4L: 121-193/193 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
DDIT4L inhibits cell growth by regulating the FRAP1 pathway upstream of the TSC1-TSC2 complex and downstream of AKT1. It is up regulated in atherosclerotic plaques relative to healthy segments of the same artery. Function: Inhibits cell growth by regulating the TOR signaling pathway upstream of the TSC1-TSC2 complex and downstream of AKT1. Subcellular Location: Cytoplasm. Tissue Specificity: Up-regulated in atherosclerotic plaques relative to healthy segments of the same artery. Similarity: Belongs to the DDIT4 family. SWISS: Q96D03 Gene ID: 115265 Database links: Entrez Gene: 115265 Human Entrez Gene: 73284 Mouse Omim: 607730 Human SwissProt: Q96D03 Human SwissProt: Q8VHZ5 Mouse Unigene: 480378 Human Unigene: 250841 Mouse Unigene: 19672 Rat |
| 產(chǎn)品圖片 |
Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (DDIT4L) Polyclonal Antibody, Unconjugated (bs-6376R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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