產(chǎn)品編號(hào) | bs-7692R |
英文名稱 | Rabbit Anti-Relaxin 1 + Relaxin 2 antibody |
中文名稱 | 松弛肽/松弛素抗體 |
別 名 | H1 antibody Preprorelaxin H1; PreprorelaxinH1; Prorelaxin; Prorelaxin H1; ProrelaxinH1; Relaxin 1 (H1); Relaxin H1; Relaxin1; Relaxin-1; RelaxinH1; RLN 1; RLN1; RLX H1; RLXH 1; RLXH1; REL1_HUMAN; REL2_HUMAN. |
研究領(lǐng)域 | 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 生長(zhǎng)因子和激素 |
抗體來(lái)源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human,Mouse,Rat) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 18kDa |
細(xì)胞定位 | 分泌型蛋白 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human Relaxin 1 and Relaxin 2: 51-150/185 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
Relaxin is a peptide hormone produced by the corpora lutea of ovaries during pregnancy in many mammalian species, including man. The secretion of the hormone into the blood stream just before parturition results in a marked softening and lengthening of the pubic symphysis and a softening of the cervix, which facilitates the birth process. By inhibiting uterine contractions, relaxin may influence the timing of parturition. Like insulin, relaxin consists of two peptide chains, A and B, covalently linked by disulfide bonds. By further analogy to insulin, the two peptides are synthesized as a single-chain precursor polypeptide with the B chain at the NH2-terminus. Function: Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals. May be involved in remodeling of connective tissues during pregnancy, promoting growth of pubic ligaments and ripening of the cervix. Subunit: Heterodimer of a B chain and an A chain linked by two disulfide bonds. Subcellular Location: Secreted Tissue Specificity: Prostate. Not expressed in placenta, decidua or ovary. SWISS: P04808 Gene ID: 6013 Database links: Entrez Gene: 6013 Human Entrez Gene: 19773 Mouse Omim: 179730 Human SwissProt: P04808 Human SwissProt: P47932 Mouse Unigene: 368996 Human Unigene: 9830 Rat |