| 產(chǎn)品編號 | bs-6391R |
| 英文名稱 | Rabbit Anti-P15RS antibody |
| 中文名稱 | 細(xì)胞周期依賴性激酶抑制相關(guān)蛋白抗體 |
| 別 名 | Cyclin dependent kinase 2B inhibitor related protein; Cyclin dependent kinase inhibitor 2B related protein (p15INK4B related protein); Cyclin dependent kinase inhibitor 2B related protein; Cyclin dependent kinase inhibitor related protein; Hypothetical protein FLJ10656; p15INK4B related protein; Putative uncharacterized protein P15RS; Regulation of nuclear pre mRNA domain containing 1A; RPRD1A; RPR1A_HUMAN. |
| 研究領(lǐng)域 | 細(xì)胞生物 細(xì)胞周期蛋白 激酶和磷酸酶 表觀遺傳學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Pig,Cow,Horse) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 36kDa |
| 細(xì)胞定位 | 細(xì)胞核 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human RPRD1A/P15RS: 231-312/312 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
P15RS is upregulated in cells overexpressing cyclin-dependent kinase inhibitor p15(INK4b) (CDKN2B; MIM 600431) and may have a role in cell cycle regulation Function: Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD. May act as a negative regulator of cyclin-D1 (CCND1) and cyclin-E (CCNE1) in the cell cycle. Subunit: Associates with the RNA polymerase II complex. Similarity: Belongs to the UPF0400 (RTT103) family. Contains 1 CID domain. SWISS: Q96P16 Gene ID: 55197 Database links: Entrez Gene: 420953 Chicken Entrez Gene: 55197 Human Entrez Gene: 225283 Mouse Omim: 610347 Human SwissProt: Q5ZM30 Chicken SwissProt: Q96P16 Human SwissProt: Q8VDS4 Mouse Unigene: 464912 Human Unigene: 28427 Mouse |
