產(chǎn)品編號 | bs-7668R |
英文名稱 | Rabbit Anti-GPR65 antibody |
中文名稱 | G蛋白偶聯(lián)受體65抗體 |
別 名 | GPCR GPR65; Dig1; G protein-coupled receptor 65; Gpcr25; GPR65; hTDAG8; Psychosine receptor; T cell death associated gene 8 protein; T-cell death-associated gene 8; TDAG8. |
Specific References (2) | bs-7668R has been referenced in 2 publications.
[IF=7.396] Daichi Mori. et al. Extracellular acidity in tumor tissue upregulates programmed cell death protein?1 expression on tumor cells via proton-sensing G protein-coupled receptors. 2021 Sep 13 FC ; mouse.
[IF=5.193] Bortell et al. Astrocyte-specific overexpressed gene signatures in response to methamphetamine exposure in vitro. (2017) J.Neuroinflammatio. 14:49 ICC,WB ; Rat.
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研究領(lǐng)域 | 細胞生物 信號轉(zhuǎn)導(dǎo) 細胞凋亡 細胞周期蛋白 G蛋白偶聯(lián)受體 G蛋白信號 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Human,Mouse,Rat |
產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 37kDa |
細胞定位 | 細胞膜 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human GPR65: 51-120/337 <Extracellular> |
亞 型 | |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
GPR65 is a member of the G protein coupled receptor family. It has been reported in human in peripheral blood leukocytes, spleen, lymph node, and thymus. The ligand for this protein is psychosine. GPR65 may have a role in activation-induced cell death or differentiation of T cells. Function: Receptor for the glycosphingolipid psychosine (PSY) and several related glycosphingolipids. May have a role in activation-induced cell death or differentiation of T-cells. Subcellular Location: Cell membrane. Tissue Specificity: Predominantly expressed in thymus, spleen, lymph nodes, small intestine, lung, placenta and peripheral blood leukocytes. Similarity: Belongs to the G-protein coupled receptor 1 family. SWISS: Q8IYL9 Gene ID: 8477 Database links: Entrez Gene: 8477 Human Entrez Gene: 14744 Mouse Omim: 604620 Human SwissProt: Q8IYL9 Human SwissProt: Q61038 Mouse Unigene: 443243 Human Unigene: 378924 Mouse |
產(chǎn)品圖片 | |